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Mold Glossary
Absidia
A zygomycete fungus. Reported to be allergenic. May cause
mucorosis in immune compromised individuals. The sites of
infection are the lung, nasal sinus, brain, eye and skin.
Infection may have multiple sites.
Acremonium(Cephalosporium)
Reported to be allergenic. Can produce a trichothecene toxin
that is toxic if ingested. It was the primary fungus identified
in at least two houses where the occupant complaints were
nausea, vomiting and diarrhea. Asexual state of Emericellopsis
sp., Chaetomium sp., and Nectripsis sp. It can produce mycetomas,
infections of the cornea and nails.
Alternaria
Aw - 0.89. Conidia dimensions: 18-83 x 7-18 microns. This is one
of the main fungal causes of allergy, being a common type I
(ex.: hay fever, asthma) & type III (ex.: hypersensitivity
pneumonitis) allergen. The large spore size suggests that this
fungus will settle in the nose, mouth, and upper respiratory
tract, causing nasal septum infections. Alternaria is a common
cause of extrinsic asthma, with acute symptoms including edema
and bronchiospasms; chronic cases may develop pulmonary
emphysema. “Baker’s asthma” is commonly associated with
inhalation of Alternaria conidia present in flour. Other
diseases caused by this mold include: “farmer’s lung”,
“woodworker's lung”, “apple store hypersensitivity”, mycotic
keratitis (fungal infection of the cornea), nasal lesions,
subcutaneous lesions, skin infections, nail infections, and
osteomyelitis (inflammation of the bone). [It should be noted
that most of the reported infections affected persons with
underlying disease or those taking immunosuppressive drugs.]
Toxic metabolites (that may cause disease in humans) produced by
these microbes include AME (alternariol monomethylether),
tenuazonic acid, and altertoxins (which are mutagenic). Several
species are pathogenic to plants, and some are processed for use
in the biocontrol of weeds and other plants. A. alternata
produces alternariol, an antifungal metabolite.
Alternaria is commonly found indoors in dust, carpeting,
textiles, on foodstuffs, and horizontal surfaces (such as window
frames). It has also been isolated from substrates such as
sewage, leather, stone monuments, optical instruments,
cosmetics, computer disks, and even jet fuel. Outdoors, it may
be found on dead organic debris, seeds, plants (and can
contribute to the spoilage of agricultural products), in soil,
and air--one of the reasons that it is a widespread genus.
Alternaria conidia are easily carried by the wind, with peak air
concentrations occurring in the summer and early fall. Colonies
grow fast, are suede-like to floccose, and black to olivaceous-black
or grayish in color.
amerospore
A spherical or oval single-celled fungal spore that is
practically unidentifiable by itself. Genera with this type of
spore include, but are not limited to, Aspergillus, Penicillium,
and Trichoderma.
For example, Penicillium is easily identifiable when sampling
using culturing techniques. However, when sampling with
non-culturing techniques, such as spore traps or tape-lifts, the
free spores with no remnants of the fungal structure are
indistinguishable from Aspergillus and various other genera that
also produce small round and oval spores with little or no
pigmentation. Due to this fact, Penicillium will often be
categorized on laboratory reports in an "amerospore" and/or "Aspergillus/Penicillium"
group.
Arthrinium
Widespread saprophyte found on decomposing plant material,
particularly grasses, and on soil. It is a white, fuzzy mold. It
should be considered to be an allergen. This fungus has also
been documented in various subcutaneous infections. No diseases
related to toxic effects have been recorded to date.
ascospore
A spore borne in a special cell called an ascus. Spores of this
type are reported to be allergenic.
All ascomycetes, members of a group of fungi called Ascomycotina,
have this type of spore. The minute black dots on rotting wood
and leaves or the little cups on lichens are examples of
ascomycetes; another is the "truffle" mushroom.
Aspergillus caesiellus
This species is only occasionally pathogenic.
Aspergillus candidus
Aw 0.75. Conidia dimensions: 2.5-4 microns. Found in warm soils,
grain and in the secondary decay of vegetation. Associated with
respiratory complaints in a recent house investigation. Can
produce the toxin petulin that may be associated with disease in
humans and other animals.
Aspergillus carneus
This species is only occasionally pathogenic.
Aspergillus clavatus
Conidia dimensions: 3-4.5 x 2.5-4.5 microns. Found in soils and
animal manure.
Can produce the toxin petulin that may be associated with
disease in humans and other animals. This species is only
occasionally pathogenic.
Aspergillus deflectus
This species is only occasionally pathogenic.
Aspergillus flavus
Aw 0.78. Conidia dimensions: 3-6 microns or 3-5 microns. It
grows on moldy corn and peanuts. It can be found in warm soil,
foods and dairy products. Some strains are capable of producing
a group of mycotoxins- in the aflatoxin group. Aflatoxins are
known animal carcinogens. There is limited evidence to suggest
that this toxin is a human carcinogen. The toxin is poisonous to
humans by ingestion. It may also result in occupational disease
via inhalation. Experiments have indicated that it is
teratogenic and mutagenic. It is toxic to the liver. It is
reported to be allergenic. Its presence is associated with
reports of asthma. It can be found in water-damaged carpets. The
production of the fungal toxin is dependent on the growth
conditions and on the substrate used as a food source. This
fungus is associated with aspergillosis of the lungs and/or
disseminated aspergillosis. This fungus is occasionally
identified as the cause of corneal, otomycotic and nasoorbital
infections.
Aspergillus fumigatus
Aw 0.82; Optimum> 0.97. Conidia dimensions: 2-3.5 microns.
Considered a human pathogen, this organism causes both allergic
aspergillosis and invasive aspergillosis (invasive aspergillosis
usually affects individuals who are immune compromised). It is
commonly found outdoors on cereal grains, in cool to warm soils,
and in compost piles (even with temperatures exceeding 40
degrees C).
Aspergillus glaucus
Conidia dimensions: 5-6.5 microns. Common outdoor fungus in the
winter. It is reported to be allergenic. This species is only
occasionally pathogenic. It can grow on leather. This fungus can
grow at low moisture levels on grains, sugary food products,
meat and wool. The ascomycetous state is Eurotium sp.
Aspergillus nidulans
Aw 0.78. Conidia dimensions: 2-4 microns. Found in mild to warm
soils and on slowly decaying plants. Can produce the mycotoxin
sterigmatocystin. This toxin has been shown to produce liver and
kidney damage in lab animals. This fungus is associated with
aspergillosis of the lungs and/or disseminated aspergillosis.
This species is only occasionally pathogenic.
Aspergillus niger
Aw 0.77; Optimum> 0.97. Conidia dimensions: 3.5 - 5 microns or 4
to 5 microns. Less common cause of aspergillosis. It has a musty
odor. It is commonly found in the environment on textiles, in
soils, grains, fruits and vegetables. It has been reported to
cause skin and pulmonary infections. It is a common cause of
fungal related ear infections, including otomycosis.
Aspergillus ochraceus
Aw 0.77. Conidia dimensions: 2.5 - 3 microns. Found in grains,
soil and salted food products. It is not usually associated with
decaying vegetation. Can produce a kidney toxin ochratoxin A
that may produce ochratoxicosis in humans. This is also known as
Balkan nephropathy. The toxin is produced at optimum growth
conditions at 25 degrees C and high moisture conditions. The
ochratoxin may also be produced by other Aspergillus sp. and
Penicillium sp. Other toxins that can be produced by this fungus
include penicillic acid, xanthomegnin and viomellein. These are
all reported to be kidney and liver toxins.
Aspergillus oryzae
This species is only occasionally pathogenic.
Aspergillus parasiticus
Some strains are capable of producing a group of mycotoxins- in
the aflatoxin group. Aflatoxins are known animal carcinogens.
There is limited evidence to suggest that this toxin is a human
carcinogen. The toxin is a poisonous to humans by ingestion.
Experiments have indicated that it is teratogenic and mutagenic.
It is toxic to the liver. The production of the fungal toxin is
dependent on the growth conditions and on the substrate used as
a food source.
Aspergillus/Penicillium-Like
This category is included on laboratory analysis reports for air
samples containing certain free spores without other identifying
structures. The free spores of Aspergillus and Penicillium (and
other genera with small, round or ovoid, and colorless spores)
are essentially indistinguishable, using standard microscopic
examination methods.
If required, cultured specimens can provide additional
characteristics that will enable technicians to determine what
genus is represented. If sporulating structures are present,
Aspergillus is readily identifiable on tape samples. [Discovery
of the Aspergillus species requires the culture of the fungus
under different conditions of media, humidity, and temperature.
Identifying Penicillium species is difficult, but, in some
cases, possible.]
These two allergenic molds are among those most often found in
contaminated buildings. Aspergillus is represented by numerous
species, many of which produce toxic substances. It may be
associated with symptoms such as sinusitis, allergic
bronchiopulmonary aspergillosis, and other allergic symptoms. As
if not to be outdone, Penicillium too is found in increased
numbers in interiors. Some of its many species produce toxic
substances that can cause allergic reactions, mucous membrane
irritation, headaches, vomiting, and diarrhea.
Aspergillus penicilloides
Conidia dimensions: 3-3.5 x 4-5 microns. Can grow in areas with
low water activity. It is found in house dust and food.
Aspergillus restrictus
This species is only occasionally pathogenic.
Aspergillus
Aw 0.75 - 0.82. Reported to be allergenic. Members of this genus
are reported to cause ear infections. Many species produce
mycotoxins that may be associated with disease in humans and
other animals. Toxin production is dependent on the species or a
strain within a species and on the food source for the fungus.
Some of these toxins have been found to be carcinogenic in
animal species. Several toxins are considered potential human
carcinogens. Common cause of extrinsic asthma (immediate-type
hypersensitivity: type I). Acute symptoms include edema and
bronchiospasms; chronic cases may develop pulmonary emphysema;
may also be associated with sinusitis, allergic
bronchiopulmonary aspergillosis, and other allergic symptoms.
Aspergillus sydowi
This species is only occasionally pathogenic.
Aspergillus terreus
Aw 0.78. Conidia dimensions: 1.8-2.4 microns or 2 - 2.5 microns.
Aleurospores 6 - 7 microns in diameter are also produced. Found
in warmer soil and in grains, straw, cotton and decomposing
vegetation. Can produce the toxin patulin and citrinin that may
be associated with disease in humans and other animals. This
fungus is associated with aspergillosis of the lungs and or
disseminated aspergillosis. Found as an isolate from otomycosis
- ear infection, and onychomycosis - infection of finger or
toenails.
Aspergillus ustus
This species is only occasionally pathogenic.
Aspergillus versicolor
Aw 0.78. Conidia dimensions: 2-3.5 microns. Mostly in temperate
zones, it is commonly found in air, house dust, foods (including
dairy products), soil, hay, and cotton. It sometimes produces
the mycotoxin "sterigmatocystin", which can cause diarrhea and
upset stomach, and is a possible carcinogen, affecting the liver
and kidneys. Various other toxins are associated with A.
versicolor, such as aspercolorin, averufin, cyclopiazonic acid,
and versicolorin. Additionally, the volatile organic compound
(VOC) "geosmin" is generated by the action of this mold. Often
an irritant to mucus membranes of humans and pets, geosmin has a
musty, earthy odor.
Aureobasidium
Found in soil, forest soils, fresh water, aerial portion of
plants, fruit, marine estuary sediments, wood. Allergen, Type I
allergies (hay fever, asthma). Type III hypersensitivity
pneumonitis: "humidifier fever", "sauna taker's lung". Growth
indoors is widespread where moisture accumulates- especially
bathrooms and kitchens- on shower curtains, tile grout,
windowsills, textiles, liquid waste materials. Potential toxic
production is not known. Rare reports of: isolates from skin
lesions, keratitis, spleen abscess in a lymphoma patient, blood
isolate from a leukemic patient.
Basidiomycetes
Taxonomic designation for fungi of the subdivision "Basidiomycotina",
which includes mushrooms and puffballs. They produce spores that
are formed on the outside of a special cell, called the "basidium".
basidiospore
An exogenous sexual spore (meiospore) borne on a basidium. Or, a
spore from a basidiomycete (a member of Basidiomycetes). Many
varieties are reported to be allergenic.
Bipolaris
A fungus with large spores that could be expected to be
deposited in the upper respiratory tract. This fungus can
produce the mycotoxin - sterigmatocystin, which has been shown
to produce liver and kidney damage when ingested by laboratory
animals.
Blastomyces
Human pathogen. The fungus is commonly found in soil. It is a
dimorphic fungus that has filamentous fungus when grown at 25
degrees C. and a yeast form at 37 degrees C.
Botrytis
Aw 0.93. Conidia dimensions: 7-14 x 5-9 microns. It is parasitic
on plants and soft fruits. Found in soil and on house plants and
vegetables, it is also known as "gray mold". It causes leaf rot
on grapes, strawberries, lettuce, etc. It is a well-known
allergen, producing asthma type symptoms in greenhouse workers
and the symptoms of "wine grower's lung".
Candida
Part of the normal flora of mouth and other mucous membranes in
the body. Thrush and other diseases caused by Candida albicans
usually occur after prolonged treatment with antibiotics or
steroids. The environment is not a likely source of exposure for
this fungus. Cells from the organism are usually not airborne.
Reported to be allergenic.
Cephalosporium
See Acremonium
Chaetomium
Large ascomycetous fungus producing perithecia. It is found on a
variety of substrates containing cellulose, including paper and
plant compost. It has been found on paper in sheetrock. It can
produce an Acremonium-like state on fungal media. Varieties are
considered allergenic and have been associated with peritonitis,
cutaneous lesions, and system mycosis.
Cladosporium fulvum (Fulvia fulva)
Conidia dimensions: 12-47 x 4-10 microns. It is found on the
leaves of tomatoes.
Cladosporium herbarum
Aw 0.88. Conidia dimensions: 5-23 x 3-8 microns. It is found on
dead plants, woody plants, food, straw, soil, paint and
textiles.
Cladosporium macrocarpum
Conidia dimensions: 9-29 x 5-13 microns. It is found on dead
plants, woody plants, food, straw, soil, paint, and textiles.
Cladosporium (Hormodendrum)
Aw 0.88; Aw 0.84. Most commonly identified outdoor fungus. The
outdoor numbers are reduced in the winter. The numbers are often
high in the summer. Often found indoors in numbers less than
outdoor numbers. It is a common allergen. Indoor Cladosporium
sp. may be different than the species identified outdoors. It is
commonly found on the surface of fiberglass duct liners in the
interior of supply ducts. A wide variety of plants are food
sources for this fungus. It is found on dead plants, woody
plants, food, straw, soil, paint, and textiles. Produces greater
than 10 antigens. Antigens in commercial extracts are of
variable quality and may degrade within weeks of preparation.
Common cause of extrinsic asthma (immediate-type
hypersensitivity: type I). Acute symptoms include skin lesions,
eye ulceration, mycosis (including onychomycosis, an infection
of the nails of the feet or hands) edema and bronchiospasms;
chronic cases may develop pulmonary emphysema.
Cladosporium sphaerospermum
Conidia dimensions: 3-4.5 microns. It is found as a secondary
invader of plants, food, soil, paint and textiles.
conidium
A thin-walled, asexual spore borne exogenously on an often
specialized hypha (conidiophore) and is deciduous at maturity.
(plural form: conidia.)
conidia, unidentified
These are mold spores that do not show morphological
characteristics that allow identification. Because there are
tens of thousands of types of fungi, many fall into the "other"
or "unknown" category. If they are present in significant
numbers, additional measures can be taken to identify them. When
spore counts are listed in the category: "Unidentified Conidia"
their numbers are considered "normal".
Conidobolus
Can cause a chronic inflammatory disease of the nasal mucosa (entomophthoromycosis).
Cryptococcus neoformans
A basidiomycetous encapsulated fungal organism found worldwide,
mainly around pigeon roosts and soil contaminated with decaying
pigeon or chicken droppings. It is generally accepted that the
organism enters the host by the respiratory route in the form of
a dehydrated haploid yeast or as basidiospores. Hematogenously
spreading to extrapulmonary tissues, its predilection for the
brain means infected persons usually contract
meningoencephalitis, which can be fatal.
Cryptostroma corticale
Conidia dimensions: 4-6.5 x 3.5-4 microns. Found on the bark of
maple and sycamore trees and on stored logs.
Cunninghamella
Can cause disseminated and pulmonary infections in immune
compromised hosts.
Curvularia
Reported to be allergenic and has been associated with allergic
fungal sinusitis. It may cause corneal infections, mycetoma, and
infections in immune compromised hosts.
Dictyosporium
A fungal genus of the classification group "Hyphomycetes". At
this time, there is no information available concerning
Dictyosporium allergenicity or toxicity, but as a member of the
classification group "Dematiaceous Hyphomycetes", it could
potentially cause phaeohyphomycosis (see phaeohyphomycosis). It
is found in terrestrial and freshwater habitats, and is a common
saprobe of submerged lignocellulose substances. The microscope
reveals its spores to be multicellular and tongue-shaped; with
subconcentric cells. Colonies may appear dark brown,
green-black, or black.
Dreschlera
Conidia dimensions: 40-120 x 17-28 microns. Found on grasses,
grains and decaying food. It can occasionally cause a corneal
infection of the eye.
Epicoccum
Conidia dimensions: 15-25 microns. A common allergen. It is
found in plants, soil, grains, textiles and paper products.
Epidermophyton
Can cause infections of skin (including ringworm) and nails.
fungus
Neither animals nor plants, these saprophytic and parasitic
spore-producing organisms rate a taxonomic kingdom of their own.
Fungi include molds, rusts, mildews, smuts, mushrooms,
puffballs, and yeasts. It is estimated that more than 1.5
million species of fungi exist.
Fusarium solani
Aw 0.90. Macroconidia dimensions: 27-52 x 4.4-6.8; Microcondia
dimensions: 8-16 x 2-4 microns. Found in plants and soils. Can
produce trichothecene toxins that may be associated with disease
in humans and animals.
Fusarium
Aw 0.90. A common soil fungus. It is found on a wide range of
plants. It is often found in humidifiers. Several species in
this genus can produce potent trichothecene toxins. The
trichothecene (scirpene) toxin targets the following systems:
circulatory, alimentary, skin, and nervous. Produces vomitoxin
on grains during unusually damp growing conditions. Symptoms may
occur either through ingestion of contaminated grains or
possibly inhalation of spores. The genera can produce
hemorrhagic syndrome in humans (alimentary toxic aleukia). This
is characterized by nausea, vomiting, diarrhea, dermatitis, and
extensive internal bleeding. Reported to be allergenic.
Frequently involved in eye, skin, and nail infections.
Geotrichum
Aw 0.90. Conidia dimensions: 6-12 x 3-6 microns. Aw 0.90. A
common contaminant of grains, fruits, dairy products, paper,
textiles, soil, and water; often present as part of the normal
human flora. The species Geotrichum candidum can cause a
secondary infection (geotrichosis) in association with
tuberculosis. This rare disease can cause lesions of the skin,
bronchi, mouth, lung, and intestine.
Gliocladium
A fungus that is structurally similar to Penicillium sp. It
is reported to be allergenic.
Helicomyces
A mitosporic mold often encountered on decaying plant matter.
The genus name prefix "helico" is derived from the shape of the
mold's microscopic structure; certain filaments (sometimes the
conidia) curve into a helical path.
Reported effects upon human health in the indoor environment are
not available at this time.
Scientists have shown the interaction of Helicomyces roseus with
nitrogen-fixing bacteria to be a vital component of an effective
soil enriching system (where sugar cane litter is the
decomposition target). Helicomyces lilliputeus has long been
known as an important sewage treatment systems decomposer, so it
is not unexpected that other members of this genus have been
observed living on wood submerged in water.
Helminthosporium
Reported to be allergenic.
Histoplasma
A fungus that has filamentous growth at 25 degrees C. and yeast
growth at 37 degrees C. It is reported to be a human pathogen.
It may be associated with birds.
Humicula
Grows on products with a high cellulose
content. These fungi are also found in soil and on plant debris.
hyaline mycelia
Mycelia that are transparent, translucent, or colorless. If no
reproductive structures are present, identification is
difficult. Often associated with allergic symptoms.
Memnoniella
A cellulolytic fungus that is very closely related to
Stachybotrys sp. Both fungi have a worldwide distribution and
are often found together and are commonly found in soil. Recent
studies on mycotoxins revealed that Memnoniella echinata can
have a toxicity similar to that of some isolates of Stachybotrys
chartarum. Both produce varying amounts of simple trichothecenes.
Thus, it is suggested that Memnoniella sp. should also be
considered potentially dangerous in indoor air. The major
difference between the two fungi is that the conidia of
Memnoniella sp. are in long persistent chains while those of
Stachybotrys are aggregated in slimy heads. Also the aerodynamic
diameter of Memnoniella sp. conidia is smaller and it would be
expected to have an even greater potential to penetrate deep
into lungs than the conidia of Stachybotrys sp.
Microsporum
Causes ringworm in humans.
mold
Molds are a group of organisms that belong to the taxonomic
kingdom of Fungi. There are over 20,000 species of mold. Molds
reproduce by making spores. Mold spores waft through the indoor
and outdoor air continually. When mold spores land on a damp
spot indoors, they may begin growing and digesting whatever they
are growing on. Molds can grow on virtually any organic
substance, as long as moisture and oxygen are present.
Monilia
Reported to be allergenic. This fungus produces soft rot of tree
fruits. Other members produce a red bread mold. It is
infrequently involved in corneal eye infections.
Mucor
Often found in soil, dead plant material, horse dung, fruits and
fruit juice. It is also found in leather, meat, dairy products,
animal hair, and jute. A Zygomycetes fungus that may be
allergenic (skin and bronchial tests). This organism and other
Zygomycetes will grow rapidly on most fungal media. May cause
mucorosis in immune compromised individuals. The sites of
infection are the lung, nasal sinus, brain, eye, and skin.
Infection may have multiple sites.
mycelium
A mass of interwoven hyphae (a hypha is a filamentous part of a
fungus that usually has several cells in linear succession with
dividing walls in between) that is often submerged in soil or
organic matter or the tissues of a host.
Myxomycetes
A taxonomic designation for fungi that are included in the
category of "slime molds". They're occasionally found indoors,
but mainly reside in forested regions on decaying logs, stumps,
and dead leaves. Myxomycetes display characteristics of fungi
and protozoans. In favorable (wet) conditions they exhibit
motile, amoeba-like cells, usually bounded only by a plasma
membrane, that are variable in size and form. During dry spells,
they form a resting body (sclerotium) with dry, airborne spores.
These fungi are not known to produce toxins, but can cause hay
fever and asthma.
Nigrospora
Commonly found in warm climates, this mold may be responsible
for allergic reactions such as hay fever and asthma. It is found
on decaying plant material and in the soil. It is not often
found indoors.
Oidium
The asexual phase of Erysiphe sp. It is a plant pathogen causing
powdery mildews. It is very common on the leaves stems, and
flowers of plants. The health effects and allergenicity have not
been studied. It does not grow on non-living surfaces such as
wood or drywall.
Paecilomyces
Commonly found in soil and dust; less frequently in air. P.
variotii can cause paecilomycosis. Linked to wood-trimmer's
disease and humidifier associated illnesses. They are reported
to allergenic. Some members of this genus are reported to cause
pneumonia. It may produce arsine gas if growing on arsenic
substrate. This can occur on wallpapers covered with Paris
green.
Papulospora
These fungi are found in soil, textiles, decaying plants,
manure, and paper.
Penicillium
Aw 0.78 - 0.88. A wide number of organisms have been placed in
this genus. Identification to species is difficult. Often found
in aerosol samples. Commonly found in soil, food, cellulose and
grains. It is also found in paint and compost piles. It may
cause hypersensitivity pneumonitis, allergic alveolitis in
susceptible individuals. It is reported to be allergenic (skin).
It is commonly found in carpet, wallpaper, and in interior
fiberglass duct insulation. Some species can produce mycotoxins.
Common cause of extrinsic asthma (immediate-type
hypersensitivity: type I). Acute symptoms include edema and
bronchiospasms; chronic cases may develop pulmonary emphysema.
It may also cause headaches, vomiting, and diarrhea.
Periconia
Found in soil, blackened and dead herbaceous stems, leaf spots,
grasses, rushes, and sedges. Almost always associated with other
fungi. Rarely found growing indoors. Reportedly associated with
a rare case of mycotic keratitis.
perithecium
A fruiting body of a fungus in which some types of spores
(including ascospores) are produced. (plural form: perithecia)
Peronospora
These species are plant pathogens and the genus is one that
causes downy mildews. Peronospora is very common and is an
obligate parasite (obligate parasites cannot grow on non living
environmental surfaces) found on leaves, stems, flowers, and
fruits of living higher plants. Peronospora sp. may be
identified in air on spore trap samples since spores have a
distinctive morphology. The spores may also be seen in dust as
part of the normal influx of outdoor microbial particles. As of
this writing, allergenicity has not been studied and no
information is available regarding health effects or toxicity.
phaeohyphomycosis
A hyphomycosis (infection by a mold of the taxonomic designation
"Hyphomycetes") in which the infiltrating microbes are usually
of the mold family "Dematiaceae", and are characterized by the
coloring of their mycelium; the prefix "phaeo" means
"dusky-brown". Various forms of the disease involve different
areas of the body, such as the skin or respiratory tract.
Intrusion of the mold in the eye, brain, bone, or subcutaneous
tissue typically occurs as a result of trauma to the affected
area.
Phoma
A common indoor air allergen that can cause hay fever, asthma,
and a type of hypersensitivity pneumonitis commonly called
"shower curtain disease" (shower surfaces being among those
frequented by this fungal organism). Phoma infections in humans
also have been reported; usually affecting the immunocompromised,
they include mycotic keratitis (fungal infection of the cornea),
skin infections, and phaeohyphomycosis (see phaeohyphomycosis).
For a positive identification of this genus, the specimen must
contain the pycnidia (a round to pear-shaped fruiting structure
containing conidia) to confirm the presence of simple phialides
(a cell from which conidia are extruded). A cultured sample
would provide these components. Colonies are rapid growing,
appear powdery to velvety, and exhibit many different colors.
This mold is known to grow on butter, rice, potatoes, paint
(sometimes seen as pink and purple spots on painted walls),
cement, rubber, wood, paper, and under linoleum. In nature, the
species are found in soil, manure, on fruit, dead plants, and as
parasites on live plants.
Researchers have discovered that when Phoma macrostoma is
sprinkled onto the soil in areas with no preexisting weeds, it
acts as an earth-friendly herbicide, inhibiting the ability of
many broadleaf plants (including dandelions) to produce
chlorophyll; the young broadleaf plants turn white and die while
grass seems to be unaffected.
Pithomyces
A native of mostly tropical environments, it commonly grows on
dead plants, soil, wood, and especially the dead leaves and
grasses of livestock fodder. Pithomyces chartarum produces
sporidesmin (a piperazinedione), a mycotoxin known to cause
animal liver damage, and it causes facial eczema in cattle,
sheep, and goats. For humans, it is considered a possible
allergen, and a potential infectious agent in immunocompromised
patients.
Not known to be prolific indoors, this mold can sometimes be
found on paper. It exhibits distinctive multi-celled brown
conidia.
Rhizomucor
The Zygomycetous fungus is reported to be allergenic. It may
cause mucorosis in immune compromised individuals. It occupies a
biological niche similar to Mucor sp. It is often linked to
occupational allergy. May cause mucorosis in immune compromised
individuals. The sites of infection are the lung, nasal sinus,
brain, eye, and skin. Infection may have multiple sites.
Rhizopus
The Zygomycetous fungus is reported to be allergenic. It may
cause mucorosis in immune compromised individuals. It occupies a
biological niche similar to Mucor sp. It is often linked to
occupational allergy. May cause mucorosis in immune compromised
individuals. The sites of infection are the lung, nasal sinus,
brain, eye, and skin. Infection may have multiple sites.
Rhodotorula
A reddish yeast typically found in moist environments such as
carpeting, cooling coils, and drain pans. In some countries it
is the most common yeast genus identified in indoor air. This
yeast has been reported to be allergenic. Positive skin tests
have been reported. It has colonized terminally ill patients.
rusts (and smuts)
These fungi are associated with plant diseases. In the
classification scheme of the fungi, the smuts have much in
common with the rusts, and they are frequently discussed
together. Both groups produce wind-borne, resistant teliospores
that serve as the basis for their classification and their means
of spread. Rusts usually attack vegetative regions (i.e., leaves
and stems) of plants; smuts usually are associated with the
reproductive structures (seeds). They can cause hay fever and
asthma.
Saccharomyces
Reported to be allergenic. Baker's yeast.
Scopulariopsis
It may produce arsine gas if growing on arsenic substrate. This
can occur on wallpapers covered with Paris green. It has been
found growing on a wide variety of materials including house
dust. It is associated with type III allergy.
Sepedonium
Most easily recognized by the spores, which are colorless to
yellow, spiny, round, 1-celled, and produced singly at the ends
of short filaments. Sometimes phialides of the Acremonium or
Gabarnaudia type may also occur. A few species of Mortierella,
as well as the human pathogen Histoplasma capsulatum, produce
spores resembling those of Sepedonium. Isolated from soil, but
most commonly parasitized mushrooms.
Serpula lacrymans
Common cause of extrinsic asthma (immediate-type
hypersensitivity: type I). Acute symptoms include edema and
bronchiospasms; chronic cases may develop pulmonary emphysema.
smuts
See rusts.
Spegazzinia
This mitosporic fungus (spores develop by means of asexual cell
division) is included in the classification group "Hyphomycetes".
At this time, no information is available concerning Spegazzinia
allergenicity or toxicity. Spegazzinia spores can be identified
in air samples by their distinctive structure, and have the
potential to produce a colony within seven to ten days. Colonies
are considered relatively slow growing, and are brownish-black
to black in color. This saprobe (deriving its nourishment from
nonliving or decaying organic matter) is most commonly found in
warm-temperate to tropical areas in soil and on dead leaves,
stems, trees, and other various kinds of plant debris.
spore
The means by which molds reproduce. Spores are microscopic
(2-100 micrometers) and various shapes. Distribution can be
accomplished by a breeze, water droplet, or a person or animal
passing by. They can even be discharged by the mold (usually
under moist conditions or high humidity).
Sporobolomyces
Reported to be allergenic.
Sporoschisma
A mitosporic fungal genus of the classification group "Hyphomycetes".
At this time, no information is available concerning
Sporoschisma allergenicity or toxicity. It is known to exist on
wood and stems, and these can be submerged in fresh water.
Microscopic features include quadriseptate spores, originating
in an enclosed membrane.
Sporothrix
The species Sporothrix schenckii can cause sporotrichosis, but
usually only in individuals that are immune compromised.
Sporotrichosis is a chronic fungal infection that results when
the mold enters the body where the skin is damaged or via the
lungs. If it reaches the bloodstream, it can affect many other
parts of the body.
Sporotrichum
Reported to be allergenic. Additionally, Sporotrichum pruinosum
has been observed in the respiratory secretions of some human
patients, indicating a possible ability to colonize the
bronchopulmonary pathways. This genus does not cause
sporotrichosis (see also Sporothrix, for there is some taxonomic
confusion between these two genera).
Rarely found in cooler regions, Sporotrichum is prevalent in
warm-temperate and tropical zones, and grows (rapidly) on soils,
decaying plant matter, wet or rotting wood, grasses, and
landscaping mulch. Colonies may appear white, rosy-beige, or
orange, and have a velvety to granular texture.
Stachybotrys
Aw - 0.94 , optimum Aw ->0.98. Several strains of this mold (S.
atra, S. chartarum, and S. alternans are synonymous) may produce
macrocyclic trichothecenes (one of which is Satratoxin H) that
are poisonous by inhalation. These mycotoxins, when present, are
primarily associated with the mold's spores.
Individuals with chronic exposure to Stachybotrys's toxins
reported cold and flu symptoms, sore throats, diarrhea,
headaches, fatigue, dermatitis, hair loss, general malaise, and
psychological depression. For infants, the toxins create a
vulnerability to a serious condition called pulmonary
hemosiderosis (bleeding in the lungs) where severe bleeding can
result in coughing blood or nosebleeds, and low grade bleeding
can cause chronic coughs and congestion with anemia. People who
unknowingly handled material contaminated with this mold
described symptoms of cough, rhinitis, burning sensations of the
mouth and nasal passages, and cutaneous irritation at the point
of contact, especially in areas of abundant perspiration. The
toxins produced by this mold will suppress the immune system,
affecting the lymphoid tissue and the bone marrow. Animals
injected with macrocyclic trichothecenes exhibited the following
symptoms: necrosis and hemorrhage within the brain, thymus,
spleen, intestines, lung, heart, lymph nodes, liver, and
kidneys.
This is a dark-colored fungus that grows on building materials
with a high cellulose content and a low nitrogen content. It is
slow growing when compared to other common molds, and may not
appear to compete well in their presence. Yet, when moisture
levels are high for prolonged periods, Stachybotrys may
gradually become the dominating genus (possibly because of its
yield of mycotoxins, which are believed to be directed against
other molds and bacteria). This organism is usually difficult to
find in indoor air samples unless it is physically disturbed,
but when it does appear it is an alert to find the source, as it
will likely be found growing in abundance. Its spores--which can
be found in a gelatinous mass--will die readily after release,
but are still allergenic and can be toxigenic. Areas with a
relative humidity above 55%, and are subject to temperature
fluctuations, are ideal for toxin production.
Stemphylium
This genus is included in the taxonomic designation "Hyphomycetes".
It is a known allergen, causing Type I allergies (examples: hay
fever, asthma). Phaeohyphomycotic sinusitis has been reported in
connection with this mold. (See phaeohyphomycosis.)
Existing mainly in the temperate northern hemisphere, it can be
found in soil, moist wood or cellulose materials, on decomposing
plants, and as pathogens on living plants (leaf spots are one
example). Colonies grow rapidly, and appear velvety to cottony
in texture; coloring is light brown or olive green to black.
Though it is rare to find indoor colonization, it has been found
in dust that is transferred in from outside, including dust on
air filters.
Syncephalastrum
Can cause a respiratory infection characterized by a solid
intracaitary fungal ball.
Torula
Found outdoors in air, soil, on dead vegetation, wood, and
grasses. Also found indoors on cellulosic materials. Reported to
be allergenic and may cause hay fever and asthma.
Trichocladium
This is a widespread mitosporic (lacking a sexual state) fungus
of the classification group "Hyphomycetes". There is little
information regarding toxicity or allergenicity, but it is known
to rarely be the causative agent for human keratitis (infection
of the cornea).
Various species of this genus may be identified from indoor
sampling (one species in particular,
Trichocladium uniseptatum, is found regularly on
indoor environmental surfaces, especially wood). Outdoors, it is
found on dead wood, stems or twigs, tubers of various plants,
pine needles, other plant debris, and in soils. It is notable
that this microbe has been associated with black root rot, as an
aggressive plant pathogen.
Trichoderma
It is commonly found in soil, dead trees, pine needles, paper,
and unglazed ceramics. It often will grow on other fungi. It
produces antibiotics that are toxic to humans. It has been
reported to be allergenic. It readily degrades cellulose.
Trichophyton
Can cause ringworm, athlete's foot, jock itch, and other
infections of the skin, nail, beard and scalp. Reported to be
allergenic. Found on soil and skin.
Trichothecium
Aw 0.90. Conidia dimensions: 12-23 x 8-10 microns. Found in
decomposing vegetation, soil, corn seeds, and in flour. The
species Trichothecium roseum can produce a trichothecene toxin
that may be associated with disease in humans and other animals.
Reported to be allergenic.
Tritirachium
Reported to be allergenic.
Ulocladium
Aw 0.89. This mold is reported to be a major allergen, capable
of causing hay fever and asthma. It is also known to rarely
cause subcutaneous infections. The University of Adelaide,
Australia, categorizes this microbe in the classification group
"Dematiaceous Hyphomycetes", which includes it as a possible
causative agent of phaeohyphomycosis (see phaeohyphomycosis).
Widely distributed in nature and considered a saprobe (weak
parasite), some of its growth sites are soil, grasses, dead or
dying plants (mainly herbaceous vegetation), manure, and
compost. In interior environments it has been found on paper,
painted surfaces, gypsum board, textiles, jute, straw materials,
carpets, cellulose building materials (including wood), and in
dust and air samples. Colonies are moderately fast growing,
usually appearing olive-brown (or rusty-brown) to black (or
grayish), with a texture that is granular to velvety.
Verticillium
Conidia dimensions: 2.3-10 x 1-2.6 microns. Found in decaying
vegetation, on straw, soil and arthropods. A rare cause of
corneal infections.
Wallemia
Aw 0.75. Conidia dimensions: 2.5-3.5 microns. Found in sugary
foods, salted meats, dairy products, textiles, soil, hay and
fruits.
yeast
Various yeasts are commonly identified on air samples. Some
yeasts are reported to be allergenic. They may cause problems if
a person has had previous exposure and developed a
hypersensitivity. Yeasts may be allergenic to susceptible
individuals when present in sufficient concentrations.
~
"Aw" refers to the water activity measurement, where Aw is equal
to the relative humidity of the air surrounding the sample when
the air and the sample are at equilibrium (in an enclosed
space).
For help in finding word definitions:
http://ppathw3.cals.cornell.edu/glossary/Glossary.htm , "On-Line
Glossary of Technical Terms in Plant Pathology", provided by
Cornell University.
For additional information:
http://www.aerotechlabs.com/Infobase/resource.aspx?CatID=1 ,
"Microbial Glossary", provided by Aerotech Laboratories, Inc.
http://www.emlab.com/app/fungi/Fungi.po , "An Index of Some
Commonly Encountered Fungal Genera", provided by Environmental
Microbiology Laboratory, Inc.
http://www.dehs.umn.edu/iaq/fungus/glossary.html , "Fungal
Glossary", provided by the University of Minnesota Department of
Environmental Health and Safety.
http://www.doctorfungus.org/thefungi/description_index.htm ,
"Fungi Descriptions", provided by the DoctorFungus Corporation.
http://www.mercksource.com/ (abbreviated URL), "Dorland's
Medical Dictionary", provided by W. B. Saunders.
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